Research Associate III / Scientist I – Bioengineering & Microfluidic Assay Development
Sunnyvale, CA
We are seeking a highly skilled Research Associate III or Scientist I with a strong background in bioengineering and hands-on experience in microfluidics and immunoassay development. The ideal candidate will contribute to the design, fabrication, and integration of microfluidic systems with biochemical assays, enabling next-generation diagnostic solutions.
This position is highly interdisciplinary, interfacing with assay scientists, engineers, and product development teams to accelerate platform and reagent development for single-molecule detection.
Key Responsibilities:
- Design, fabricate, and characterize microfluidic devices for integration with biological assays (e.g., ELISA, molecular assays).
- Employ techniques such as soft lithography, photolithography, and 3D printing for device prototyping and testing.
- Integrate and optimize biological reagents and assays in microfluidic formats for quantitative biomarker detection in diverse biospecimens.
- Support bioassay development through DOE-driven optimization, reagent screening, and surface functionalization of microdevices.
- Analyze and interpret experimental data using software tools (e.g., Excel, JMP, GraphPad Prism).
- Participate in the characterization of assay components including magnetic beads, polymeric nanoparticles, and bioconjugates.
- Collaborate across R&D and manufacturing teams to assist in design transfer, scale-up, and V&V studies.
- Document procedures and results in lab notebooks and reports and present findings to cross-functional stakeholders.
Minimum Qualifications:
- BS/MS/PhD in Bioengineering, Biomedical Engineering, or a related field with 8+ years (BS/MS) or 2+ years (PhD) relevant industry or academic experience.
- Proven expertise in microfluidic system design, fabrication, and testing.
- Strong hands-on experience with biochemical assay development, including ELISA, fluorescence-based immunoassays, or PCR.
- Familiarity with surface chemistry, coatings, and bioconjugation strategies.
- Experience in working with biospecimens in a BSL-2 environment.
- Effective communication and documentation skills in English.
Preferred Qualifications:
- Skilled with fluid dynamics, microchannel behavior, and microscale transport phenomena.
- Proficiency in CAD and simulation software (e.g., COMSOL Multiphysics).
- Experience with robotic liquid handlers, automated assay platforms and microfluidic systems.
- Demonstrated ability to troubleshoot complex assay/microfluidic integration challenges.
- Knowledgeable with peptide/polymer chemistries, LC-MS and biophysics of fluorescence spectroscopy.
- Familiarity with ultrasensitive detection platforms (e.g., SIMOA, Gyrolab, MSD, or custom optofluidic systems).
- Exposure to regulated environments (GLP/GMP) and design control processes
What We Offer:
- Opportunity to join a growing, mission-driven team redefining diagnostics.
- A fast-paced, collaborative environment where innovation is encouraged.
- Competitive compensation and benefits package.
- Equal Opportunity Employer committed to diversity and inclusion.
Fluxus Inc. is a privately held development-stage medical device company located in Sunnyvale, CA, USA. The Company’s immediate focus is the development and commercialization of biochip-based detection platforms for ultra-high sensitivity diagnostics and bioanalytical applications. Our culture represents innovative, driven, and talented professionals with diverse perspectives, but one which is united on a mission to significantly and positively make a difference in healthcare.
As a member of Fluxus’ team, you would join an entrepreneurial and growing company that functions with the electricity of a startup but is led by a management team with a proven success record of 25+ years in life science tools and diagnostics. We look forward to hearing from you to learn more about your expertise and career goals. Fluxus provides a competitive benefits package and is an Equal Opportunity Employer regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law.
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